Cefixime + Ofloxacin Tablets

GATEXIM-O is a developed antibacterial solution by Healthgate, which is a comprehensive fixed dosage of Cefixime (200mg) and Ofloxacin (200mg). This two-action formula takes advantage of two different classes of antibiotics in order to provide an all-around assault against bacterial pathogens. Cefixime is a cephalosporin of the third generation that helps in interrupting the synthesis of the bacterial cell wall, whereas Ofloxacin is a powerful fluoroquinolone that acts by blocking the DNA gyrase, and hence stalling down the bacterial replication. GATEXIM-O has been specifically used in multi-pathways since it can overcome stubborn multi-drug-resistant strains, which may not be eliminated through single-antibiotic therapies, and thus, this technique forms an important part of the current treatment in infectious diseases.

Each film-coated tablet contains:

• Cefixime IP – 200 mg

• Ofloxacin IP – 200 mg

Dosage Form: Film-coated Tablet
Pharmacological Classification:

• Cephalosporin Antibiotic

• Fluoroquinolone Antibiot

Medical Uses

GATEXIM-O has clinical indications that include the management of severe and complicated bacterial infections, and these are:

• Typhoid Fever (Enteric Fever): This therapy is very effective against Salmonella typhi even in cases where conventional treatment has not been effective.
• Respiratory Tract Infections: Management of community-acquired pneumonia and acute attacks of chronic bronchitis.
• Complicated UTI: The Treatment of the persistent infection of the bladder and the kidneys.
• Intestinal Infections: The treatment of serious bacterial diarrhea and dysentery.
• Post Surgical Prophylaxis: The prevention of secondary infection of bacteria in abdominal or gynecological surgeries.

Directions to Use

The administration of GATEXIM-O is expected to be accurate to the instructions of a healthcare worker, and usually one tablet per day (twice). A light meal should be taken together with the tablet to maximize its absorption or reduce the likelihood of stomach upset. The tablet has to be swallowed in its entirety along with a glass of water. It is not advisable to crush, break, or chew the pill since the holding of the filming constitutes an imperative protection against the active substances being destroyed before their established actions, as well as concealing the unpleasant flavor of the fluoroquinolone constituent.

Precautions

• Tendon Health: Ofloxacin has been linked to a higher incidence of tendonitis and tendon rupture; a patient must not engage in intense exercise in case of pain affecting the joints.
• CNS Sensitivity: Should be cautiously used on patients who have any such history of epilepsy or other central nervous system disorders.
• Photosensitivity: Patients should avoid being in direct sunlight or under the UV lamps because this drug may amplify the risk of getting a very serious sunburn.
• Drug Interactions: Do not use GATEXIM-O with antacids with magnesium or aluminum, as they may lead to a major problem that affects the absorption of Ofloxacin.

Possible Side Effects

Although GATEXIM-O is very useful, there is a possibility that a patient will develop nausea, diarrhea, or a metallic mouth taste. Other minor side effects are dizziness, insomnia, or mild skin rashes. In the uncommon instances, this may cause severe reactions, which may include tendon pains, watery diarrhea that cannot be cured, or an allergic reaction (swelling of the lips or throat). Should any severe symptoms occur, then it should be discontinued, and emergency medical help should be sought.

Frequently Asked Questions

Q: Why should Cefixime and Ofloxacin be proven better to treat Typhoid fever?

A: Two angles of attack, bacteria, cell wall, and DNA, are significantly disadvantaged in reducing the likelihood of treatment failure and bacterial resistance.

Q: Can I use GATEXIM-O when I am already taking a regimen of daily supplements of iron or calcium?

A: You should space them out. Ofloxacin may be bound with minerals, which inhibit its absorption. GATEXIM-O should be taken two hours in the state of being without supplements.

Q: Does Healthgate guarantee the purity of the raw material used in GATEXIM-O?

A: Absolutely. Our quality IP-certified ingredients are obtained by sourcing and subjected to high standards of HPLC to make every 200/200mg tablet to the highest global standards of purity.

Q: Does GATEXIM-O use in a patient with a known history of penicillin allergy?

A: Caution is required. Some cross-sensitivity between penicillins and cephalosporins exists, although they are in different classes. Never take this drug without consulting your doctor.

Q: Why does this product of Healthgate have a warning that includes sunlight exposure?

A: Ofloxacin may cause skin sensitivity to UV sunlight. During your GATEXIM-O course, we recommend you wear protective clothing or put on high-SPF sunscreen to avoid the effects.

Q: What is the technological level of the film-coating process at Healthgate?

A: We have a coating technique that guarantees a coating of the polymer that shields the actives against oxidation, and makes the pill firm enough to withstand even tropical weather.

Q: May I quit taking the tablets when my fever is gone after a short 2 days?

A: No, the premature termination will allow the bacteria with the highest resistance to die and multiply, causing a relapse and the possibility of resistance to antibiotics. You should never leave anything unfinished.

Q: What is the environmental impact of high-potency antibiotics such as GATEXIM-O that is produced by Healthgate?

A: We use closed-loop types of filtration and state-of-the-art waste handling systems to ensure that no active pharmaceutical ingredients (APIs) are discharged in the surrounding ecosystem.