Esomeprazole + Domperidone SR Capsules

Esomeprazole + Domperidone SR Capsules

Esomeprazole + Domperidone is a class of gastrointestinal drugs that are employed to treat stomach ulcers, Zollinger-Ellison syndrome, and gastroesophageal reflux disease (GERD). The mucous layer in the stomach is normally protective against acid. Excess acid secretion in some individuals causes erosion of the mucous layer, leading to complications such as GERD, acidity, peptic ulcers, and Zollinger-Ellison syndrome.

Esomeprazole + Domperidone is a drug combination of two drugs: Esomeprazole (proton pump inhibitor) and Domperidone (dopamine antagonist). Esomeprazole inhibits an enzyme known as the gastric proton pump, which is involved in acid production. Domperidone inhibits the movements and contractions of stomach muscles. Esomeprazole + Domperidone, when used together, aids in treating acidity-related issues.

Benefits:

• Esomeprazole + Domperidone is indicated for the treatment of gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, and peptic ulcers. It can also be prescribed in the treatment of nausea, vomiting, bloating of the stomach, belching, heavy bloating, heartburn, acidity, gas, pain in the upper abdomen, erosive oesophagitis, and difficulty in swallowing.
• Esomeprazole is a proton pump inhibitor that inhibits an enzyme termed the gastric proton pump, which is responsible for acid secretion.
• Domperidone is a dopamine blocker that functions by enhancing the stomach muscle movements and contractions.

Uses:

Domperidone + Esomeprazole is applied in the treatment of gastroesophageal reflux disease (acid reflux) as well as functional dyspepsia. It aids in treating nausea, vomiting, heartburn, abdominal pain, and difficulty swallowing.

Directions to use:

• Read all the instructions before taking this medicine.
• Gulp it the with a whole glass of water.
• Do not break or chew this capsule.
• Take this medicine after the prescription of your physician.
• Retain this medication in a cool and dry place.

Doses:

Have this medicine in the accurate dose as suggested by your healthcare expert. Do not take it in an overdose, otherwise it may cause several side effects. Read all the instructions thoroughly before taking this medicine. To gain more benefit, take this medicine same time daily.

Storage:

• Keep these drugs (medicine) in a dry and cool place. 
• Do not keep this medicine in front of direct sunlight.
• Keep these capsules away from the reach of children and pets.

Side Effects:

• Dry mouth
• Stomach pain
• Diarrhoea
• Headache
• Flatulence
• Constipation

Precautions:

• You have been given Domperidone + Esomeprazole for the management of acidity and heartburn.
• Take this capsule an hour before the meal, mainly in the morning.
• It is a well-tolerated drug and gives relief for a considerable amount of time.
• Ask your physician if you get a fever, watery diarrhea, or stomach pain that does not go away.
• Inform your doctor if you don’t feel better after 14 days of taking it because you might be having some other issue which requires treatment.
• Long-term use will lead to weak bones and mineral deficiency like magnesium. Take proper dietary intake of calcium and magnesium or supplements as your doctor suggests.

Frequently Asked Questions (FAQ):

Q. At what time should Domperidone + Esomeprazole be taken?

It should be taken with Domperidone + Esomeprazole before the initial meal of the day or when empty.

Q. Can the use of Domperidone + Esomeprazole cause abnormal heartbeat?

Yes, Domperidone + Esomeprazole can increase the risk of abnormal heartbeat (severe arrhythmias). This is a severe side effect, but the likelihood that it will occur is extremely low. The risk is somewhat higher in patients aged over 60 years.

Q. What are the contraindications for the administration of Domperidone + Esomeprazole?

Domperidone + Esomeprazole is regarded as unsafe for patients with a history of hypersensitivity to rabeprazole or domperidone, or any other inactive components of the drug. Use this medicine with caution in patients who suffer from kidney or liver disease.