Piperacillin & Tazobactum Injection
Piperacillin + Tazobactam is classified under the ‘Antibiotics’ medication class, which is mainly prescribed to heal bacterial infections. It is prescribed for the treatment of several hospital-acquired and ventilator-associated pneumonias, urinary tract infections, intra-abdominal infection, skin and soft tissue infection (such as diabetic foot infection), and uterine infection. Bacterial infection is a condition in which dangerous bacteria develop in the body and make it ill. It can infect any region of the body and double in no time.
Piperacillin is a member of the class ‘Penicillin antibiotics.’ It is bactericidal (bacterial killing) in action against gram-positive and gram-negative aerobic (oxygen-requiring) and anaerobic (little or no oxygen) bacteria. Piperacillin exerts its effect by binding to the penicillin-binding proteins (PBPs) within the bacterial cell wall and preventing its cell wall synthesis. Tazobactam is a beta-lactamase inhibitor. Beta-lactamases are the bacteria-produced enzymes to achieve multi-resistance to β-lactam antibiotics, like penicillins and cephalosporins. Tazobactam inhibits the degradation of other antibiotics by beta-lactamase-producing organisms.
Benefits:
- Piperacillin is an antibiotic of Penicillin. It inhibits by binding to penicillin-binding proteins (PBPs) within the bacterial cell wall and blocks its cell wall synthesis.
- Tazobactam is a beta-lactamase inhibitor, which stops the degradation of other antibiotics by beta-lactamase enzyme-secreting organisms.
- In Piperacillin + Tazobactam, Tazobactam inhibits bacteria from destroying Piperacillin.
- Piperacillin + Tazobactam treats several bacterial infections of the uterus, lungs, skin, and stomach.
Uses:
- Piperacillin + Tazobactam is used to treat severe intra-abdominal infections by fighting the causative bacteria.
- Piperacillin + Tazobactam is administered to treat serious respiratory infections, such as pneumonia.
- Piperacillin + Tazobactam is used to treat complex skin and soft tissue infections caused by surgical wounds, bites, or diabetic foot.
- Piperacillin + Tazobactam is utilized to treat severe infections in females, such as pelvic inflammatory disease and endometritis, by acting on a wide spectrum of bacteria.
Directions to Use:
- Administer this injection after consultation with your healthcare expert.
- Read all the instructions carefully before taking this injection.
- Place this injection in a room temperature or a cool place.
- Administer this injection after having a meal.
- Do not administer an overdose of this injection.
Storage:
Store this injection in a room temperature or a cool place. Do not place this in front of direct sunlight and place this away from he reach of children and pets.
Dosage:
Administer this injection in an accurate dosage as prescribed by your physician. Do not self-administer this injection. If you administer this in an overdose, you will suffer from several side effects of this drug.
Side Effects:
- Nausea
- Constipation
- Diarrhoea
- Headache
- Trouble sleeping
Precautions:
- You have been given this combined medicine to cure bacterial infections even when they are resistant.
- Complete the course as prescribed, even if you begin to recover. To stop it too early might allow the infection to recur and more difficult to treat.
- Diarrhea is a possible side effect. Probiotics taken with Piperacillin + Tazobactam might help. Contact your doctor if you observe bloody stools or experience abdominal cramps.
- Discontinue Piperacillin + Tazobactum and tell your doctor right away if you experience an itchy rash, face, throat or tongue swelling or breathing problems while receiving it.
- Never use leftover medication to cure any infection going forward. Before using an antibiotic, always consult your doctor.
Frequently Asked Questions (FAQ):
Q. What are the contraindications for the administration of Piperacillin + Tazobactam?
Use of Piperacillin + Tazobactam must be avoided in patients with known allergy to any of the ingredients or excipients of this drug.
Q. What if I overdose?
If you overdose Piperacillin + Tazobactam, you can be affected by severe anxiety, nervousness, or restlessness, or convulsions (seizures). Inform your healthcare expert frequently if you observe any of these.
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