Ursodeoxycholic Acid 300 mg Tablets

Ursodeoxycholic Acid 300 mg Tablet contains ursodeoxycholic acid (UDCA), which is a naturally occurring bile acid that is indicated for the treatment of cholestatic liver diseases, dissolution of selected cholesterol gallstones, and improving bile flow. It helps to preserve the liver’s cells, lower the level of bile acid toxicity, and keep the liver functioning properly.

Uses Of Ursodeoxycholic Acid 300 mg Tablet

• A group of inflammatory conditions of the liver that are autoimmune (PBC).
• Small to medium sized gallstones with cholesterol in them (cholesterol containing stones)
• Complications associated with gallstone formation can be prevented during the process of very rapid weight loss.

Benefits Of Ursodeoxycholic Acid 300 mg Tablet

Cholestatic liver diseases

• Cystic Fibrosis Liver Disease in Pediatric (Children ages 6-18) population
• To be taken at any time, taken to help bile flow, taken at bedtime.
• The tablets of ursodeoxycholic should be taken after meals with water or milk.
• Your doctor will determine your dose according to your illness and weight.
• The recommended dosage is 10-15 mg/kg/day divided into 2-4 doses.
• The treatment for gallstones can take up to two years and should be extended for three months following dissolution of the stones.

Ursodeoxycholic Tablets Side effects

Some of the lesser known side effects include:

• Diarrhoea
• Abdominal pain
• Nausea
• Indigestion
• Skin rashes
• Dizziness
• Fast heartbeat

Precautions

• The medication’s absorption decreases with aluminum-containing antacids, charcoal, cholestyramine, or colestipol.
• During treatment, your doctor will need to check on how your liver is functioning on a regular basis.
  This medicine should not be given to anyone who has low tolerance for gallbladder inflammation or obstruction.
• Do not give this medicine to people who are able to tolerate acute inflammation of the gallbladder or blocked bile duct.
• Pregnant & breastfeeding women should consult their doctor before taking this medicine.
• Ursodeoxycholic Acid Tablet is what it takes to help with the symptoms of primary sclerosing cholangitis.

May be used with Other Medicines?

This medicine interacts with a various drugs including:

• Aluminium-containing antacids
• Ciclosporin
• Ciprofloxacin
• Cholestyramine
• Colestipol
• Nitrendipine
• Rosuvastatin

Dosing Information

Dosage will depend on your condition:

• For dissolution of gallstones, 8-10mg:kg daily divided into 2-3 doses.
• For primary biliary cirrhosis, the dosage is 13-15 mg/kg/day, broken down into 2-4 doses.
• The dosage for weight reduction as well as prevention of gallstones is 300 mg every day, 2 x per day.
• The optimal dose for PBC (primary biliary cirrhosis) is 900 mg/day (up to approximately 13.5 mg/kg/day).

FREQUENTLY ASKED QUESTIONS ( FAQ )

Does ursodeoxycholic acid present any special dangers?
UOA is well tolerated and has good safety profile. Medication will be used at the normal dose 13-15 mg/kg/day, and will not be harmful to most approved uses. These may be harmful in people receiving high doses of aciprol (28–30 mg/kg/day) and particularly if you are also suffering from primary sclerosing cholangitis.

Which is the primary indication to use ursodeoxycholic acid?
The best benefit of the medication is that it is used in the treatment of cholestatic liver diseases

At what time of the day should definitive ursodeoxycholic acid be taken – morning or evening?
Evenings’ doses are often prescribed to flush out gallstones. The last dose should be taken at bedtime for twice-daily prescriptions to work best. Always follow your doctor’s instructions regarding the timing.

What’s the time gap between ursodeoxycholic acid and its effects?
Liver function tests start showing improvements after 3-4 weeks. Dissolving gallstones is a slower process, and may take anywhere from 6 months to 24 months or longer, depending on the size and type of stone.

Is ursodeoxycholic acid good for the liver?
Yes, it is. Medication will help to prevent liver cells being damaged and lower toxic bile acids. There is increased flow of bile through your liver and a decrease in several enzymes such as alkaline phosphatase, AST, ALT and GGT.

What do I do if I forget to take my medicine?
The missed dose should be taken right after it is remembered. Take the missed dose as soon as it is remembered, if the next dose is within 4 hours, or as soon as it can be taken, provided that the missed dose is not followed by a double dose. Taking a double dose won’t help compensate.

What will happen if I overdose?
A lot of the main symptoms of an overdose include diarrhoea. If you think you might have an overdose, call emergency medical staff immediately. Treatment is aimed at symptom control, and correcting fluid balances.